Myristoyl Hexapeptide-4 is a hydrophilic peptide rich in the essential amino acid threonine with sequence Myr-Thr-Lys-Thr-Thr-Lys-Ser-NH2, which is more bioactive, thanks to modifications during production. It is known under the trade name SymPeptide® 230.
Peptides
There are numerous examples in physiology of peptide regulatory elements that play integral roles in basic homeostatic mechanisms such as injury-repair responses and other stimulus-response actions. Among these are well-known neuropeptides (e.g., bradykinins, endorphins); metabolism and fat storage regulators (e.g., neuropeptide Y, leptin, insulin); tanning and skin pigmentation-related peptides (e.g., α-MSH, ACTH, Agouti), and peptides involved in wound healing (e.g., FGF).
This large group of innovative cosmeceutical ingredients triumphed in the world of skincare products during the last two decades. Peptides are chains of amino acids that are attached in a specific order. Amino acids are naturally occurring in the body and are vital to everyday living processes. Peptides can be made up of 2 or more amino acids that can stimulate different responses within the body. As a result, peptides serve as tiny messengers that can be sent to kick the skin into gear and make it look better.
Peptides are leading a beauty revolution due to their excellent multi-functional properties; formularies are scrambling to access the latest advances in cosmetic peptide technology. In addition, their "Botox-like" performance, activation of collagen and elastin production, and skin-lightening effect make them very efficient against coarse wrinkles and hyperpigmentation of the skin.
Myristoyl Nonapeptide-3 is a synthetic biomimetic lipo-peptide with retinol-like action, known under the trade name RetinoPeptide™ 189. Mimicking famous anti-aging vitamin A's biological activity boosts collagen type I production, exposing a firmer, smoother, and youthful appearance.
Myristoyl Octapeptide-1 is a synthetic lipo-peptide that mimics growth factors, promoting dermal tissue repair processes and accelerating wound healing. It binds to the specific receptors on fibroblasts, boosting skin cell proliferation and activity.
Myristoyl Pentapeptide-17 is a bioavailable lipo-oligopeptide (sequence Myr-Lys-Leu-Ala-Lys-Lys-NH2) with eyelash-enhancing action. In addition, it has anti-aging, anti-inflammatory, and anti-bacterial properties.
Myristoyl Pentapeptide-4 (formerly Myristoyl Pentapeptide-3) is a synthetic lipo-peptide sold under the trade name Collasyn 514KS, an ester of Myristic acid (attached to the N-terminus) and KTTKS peptide with sequence Myr-Lys-Thr-Thr-Lys-Ser.
Myristoyl Pentapeptide-8 is a synthetic matrikine lipopeptide that mimics the action of cell-adhesion proteins, resulting in a smoother, healthier, and more resilient skin appearance.
Myristoyl Tetrapeptide-12 is a synthetic lipo-peptide with sequence Myr-Lys-Ala-Lys-Ala-NH2 specially developed for improving the appearance of eyelashes and eyebrows. It promotes hair growth and provides a thicker, longer, and voluminous appearance.
Myristoyl Tetrapeptide-13 is a synthetic amphiphilic cationic lipopeptide with potent antimicrobial activity. It has the sequence Myr-Lys-Lys-Ala-Leu-NH2 and is known under the trade name Dermalysins® P291.
Indoor tanning provides a year-round, convenient, controlled environment for people of all types who want to enjoy the look and feel of a tan body. Myristoyl Tetrapeptide-20 is a topically active short peptide that exerts effective tanning without harmful UV irradiation.
Myristoyl Tetrapeptide-34 is an anti-aging lipopeptide that has been developed to inhibit UV-induced matrix-degrading MMPs and to restore collagen quantities to normal levels.
Myristoyl Tetrapeptide-6 is a synthetic lipopeptide that inhibits human neutrophil elastase (HSE) and exhibits anti-aging properties. It has the sequence Myr-Ala-Ala-Pro-Val (mAAPV) and is known under the trade name DermaPep™ A420.
Myristoyl Tripeptide-31 is a synthetic multifunctional lipopeptide with retinoid-like anti-aging effects on the skin. It has the sequence Myr-Gly-Leu-Phe and is known under the trade name DermaPep™ A350.
N‑Prolyl Palmitoyl Tripeptide‑56 Acetate is a synthetic matrikine lipopeptide with firming and anti-aging properties, known under the trade name (used in peptide-based complex) Matrixyl® Morphomics™.
Some neuropeptides produced locally, within the skin, have natural anti-inflammatory activities. Proopiomelanocortin (POMC), a neuroendocrine protein found in the skin in response to local stressors, is an important precursor of such neuropeptides.
Nicotinoyl Dipeptide-23 is a vitamin-peptide conjugate niacinamide (Vitamin B3) introduced into the N-terminus of peptide through chemical synthesis. It is known under the trade name V-peptide-2.
Octapeptide-11 is a synthetic peptide with sequence Met-Ile-Pro-Cys-Tyr-Ile-Ser-Ser known under the trade name CG-Seperin. It acts as an inhibitor of the MMP (Matrix MetalloProteinase) enzyme responsible for hyaluronic acid degradation.
Octapeptide-2 is a synthetic peptide that strengthens hair and promotes its growth. It is also known under the trade name Prohairlin-β4.
Octapeptide‑30 (known as Octa-His) is a synthetic peptide composed of eight histidine units.
Oleoyl Dipeptide-15 (Glycyl glycine oleamide) is a synthetic lipopeptide that fights against skin structural proteins glycation and elastosis. It is known under the trade name Relastide®.
Oligopeptide-10 is a 15-amino-acid-long peptide with the sequence Phe-Ala-Lys-Ala-Leu-Lys-Ala-Leu-Leu-Lys-Ala-Leu-Lys-Ala-Leu. It is a water-soluble white powder, compatible with all emulsion types in the 5-7 pH range.
Oligopeptide-104 is a synthetic 11 amino acid-long peptide with sequence Ac-Gln-Gln-Arg-Phe-Glu-Trp-Glu-Phe-Glu-Gln-Gln-NH2 that self-assembles into a 3D matrix with multiple calcium-binding sites as a nucleation point for Hydroxyapatite, triggering the natural tooth regenerative,
Oligopeptide-177 is a 33-amino-acid-length synthetic peptide whose sequences repeat a fragment of the erythropoietin (EPO) glycoprotein. It is a non-erythropoietic erythropoietin-derived peptide.
Oligopeptide-18 is a synthetic peptide that promotes hair removal by inhibiting the maturation of hair follicle cells. This peptide is also known under the trade name Retadrin.
Oligopeptide-19 is a synthetic peptide that fights against unwanted hair by slowing down hair follicle cell maturation. This peptide is also known under the trade name Alopectin.
Oligopeptide-20 is a synthetic peptide that mimics Somatomedin (Insulin-like growth factor 1; IGF1), involved in normal skin growth, healing, and wound repair.
Oligopeptide-21 is a synthetic peptide developed for the reduction and prevention of lines and deep wrinkles. This peptide is also known under the trade name CG-IDP 4.
Oligopeptide-22 is a synthetic peptide with anti-wrinkle, anti-aging, and wound-healing properties. It is known under the trade name CG-IDP 3.
Oligopeptide-24 (formerly Oligopeptide-23; known under the trade name CG-EDP3) is a synthetic biomimetic peptide that stimulates skin cell proliferation by up-regulation of EGF (Epidermal Growth Factor) expression.
Oligopeptide-34 is a synthetic peptide that decreases melanin synthesis by down-regulation of TRP-1, TRP-2, MITF, and Tyrosinase. It also blocks melanosome assembly and its transfer from melanocytes to keratinocytes, leaving a significant skin-brightening effect.