Peptides
Acetyl Hexapeptide-38 is a synthetic peptide (with sequence Ac-Ser-Val-Val-Val-Arg-Thr-NH2) found with screening methods and using the reporter gene assay from millions of other hexapeptides with different
The skin is facing many kinds of stress, such as aging, mycobacterium and virus attack, UV and infrared light, and recently issued environmental stress, such as pollen, PM2.5, and PM10, including its harmful components polycyclic aromatic hydrocarbons (PAHs) and heavy metals.
Biotinoyl Hexapeptide-2 Amide is a conjugate of Hexapeptide-2 and biotin (vitamin B7), providing a synergic effect of those superstar ingredients. It is known under the trade name Biotide2000.
Cyclohexpeptide-90 is a synthetic cyclic hexapeptide that increases BiP and Calreticulin protein production, chaperones in the endoplasmic reticulum responsible for proteins properly folding. This peptide is known under the trade name Poptide™.
It is well known that skin pigmentation is mainly affected by three major signaling pathways; α-MSH/MC-1R, ET-1/ETBR, and SCF/c-kit.
Hexacarboxymethyl Dipeptide-12 is a peptide derivative that acts as a direct activator of Sirtuin1 (SIRT1). SIRT1 is an NAD+-dependent deacetylase enzyme that regulates cellular metabolism, survival, and lifespan. It deacetylates the target protein FoxO1, initiating cell autophagy.
Palmitoyl Dipeptide-17 (Palmitoyl Glycylproline) is a synthetic lipopeptide with the sequence Pal-Gly-Pro. It is known under the trade name Proliphil.
Tetracarboxymethyl Hexanoyl Dipeptide-12 is a synthetic peptide derivative that enhances the expression of genes responsible for adiponectin production while inducing dermal cells' protective autophagy. It is also known under the trade name AdipoSOL™ 2000.