Acetyl Decapeptide-3 is a synthetic peptide (known under the trade name CG-Rejuline) that repeats the part of the sequence (Ac-tyr-arg-ser-arg-lys-tyr-thr-ser-trp-tyr-NH2; YRSRKYTSWY) of bFGF - Basic Fibroblast Growth Factor (or Fibroblast growth factor 2; FGF-β) protein and mimics its function.
bFGF is typically involved in skin development, wound healing, and regeneration, promoting the growth and proliferation of fibroblasts, endothelial cells, and keratinocytes. It also protects cells from apoptosis.
Besides skin cell proliferation and renewal, Acetyl Decapeptide-3 increases the expression levels of extracellular matrix proteins, including collagen, fibronectin, and laminin. It reduces the appearance of fine lines and wrinkles, improves elasticity, and makes skin firmer and suppler.
During clinical tests, Acetyl Decapeptide-3 exhibited greater stability and a prolonged action compared to naive bFGF. In addition to its anti-aging and anti-wrinkle effects, CG-Rejuline also promotes hair growth, strengthens follicles, and stimulates the development of new cells.
