sh-Polypeptide-19

sh-Polypeptide-19 (former rh-Oligopeptide-3 and rh-Polypeptide-19) is a synthetic single-chain recombinant peptide, an analog of human TGF-α (Transforming Growth Factor-α). TGF-α boosts the generation and migration of keratinocytes, accelerates wound healing, and improves skin tone.

In addition, sh-Polypeptide-19 stimulates the renewal of nerve endings and the growth of axons from damaged nerve fibers. It helps improve innervation, blood supply, and skin nutrition, thereby prolonging the active period of the cell cycle.

Applied topically, sh-Polypeptide-19 reduces the appearance of expression lines and wrinkles while preventing new line formation. In addition, it helps fight scars and promote wound healing, preventing scar tissue formation.

Preparations containing sh-Polypeptide-19 activate recovery processes after peelings, fractional thermolysis, and plastic surgery. It is a safe, effective anti-aging ingredient for high-end modern skin and body care formulations. However, it mimics a growth factor whose overexpression is correlated with tumorogenesis or tumor progression; therefore, products containing this peptide should be used strongly according to recommendations and doses.