Acetyl Octapeptide-17 Amide

Functions
Anti-aging
Firming
Smoothing
Regeneration booster
INCI name
Acetyl Octapeptide-17 Amide

Acetyl Octapeptide-17 Amide is a synthetic peptide that mimics a functional part of EGF (Epidermal Growth Factor) with the sequence Ac-Met-Leu-Lys-Glu-Trp-Glu-Leu-Arg-NH2. It is known under the trade names Dermacurin and Mini EGF.

Thanks to its low molecular weight, Acetyl Octapeptide-17 Amide has an excellent skin permeation rate and enhanced stability compared to the wild-type EGF, which contains 53 amino acids. It binds to the EGF receptor, promoting epithelial cell proliferation and stimulating fibroblasts' collagen production.

With aging, the concentration of growth factors, including EGF, decreases, leading to slower regeneration, reduced elasticity, and the formation of wrinkles. Applied topically, Acetyl Octapeptide-17 Amide boosts skin regeneration, helping fight signs of aging, increase elasticity, and improve appearance.

Synonyms
Mini EGF
Dermacurin
EGF octapeptide
Changed

References

Recent advances in the epidermal growth factor receptor/ligand system biology on skin homeostasis and keratinocyte stem cell regulation
Author(s):
, , ,
PMID:
23819985
DOI:
10.1016/j.jdermsci.2013.05.009
Challenges and effective routes for formulating and delivery of epidermal growth factors in skin care
Author(s):
,
DOI:
10.1111/ics.12685