Oligopeptide-20 is a synthetic peptide with the sequence Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro that contains 12 amino acids and mimics Somatomedin (a growth factor) involved in normal skin growth, healing, and wound repair. It increases cell proliferation of skin keratinocytes and fibroblasts, activating and accelerating the restoration of damaged skin.
Oligopeptide-20 strengthens the walls of microvessels in vegetative-vascular dystonia, evens out skin tone, and rebuilds skin layers. It thickens the epidermis and dermal structures, promoting skin tightening.
Boosting collagen and elastin production, Oligopeptide-20 improves skin elasticity, suppleness, and firmness. The topical application reduces lines and wrinkles, helping to prevent their formation.
Oligopeptide-20 showed positive regulation of collagen and elastin, and fibronectin expression. Increased expression of collagen (1.4-fold), fibronectin (4.3-fold), and elastin (1.4-fold) was observed in fibroblast cell cultures. It is used in products for sensitive, atopic skin and anti-aging serums.
