Decapeptide-4

Functions
Anti-aging
Firming
Smoothing
Sliming
Regeneration booster
Hair growth stimulator
CAS Number(s)
2227218-71-3
INCI name
Decapeptide-4
Origin
Synthetic

Decapeptide-4 is a synthetic peptide known under the trade name CG-IDP2 that mimics the Somatomedin C (IGF-1) growth factor involved in normal skin growth, healing, and wound repair. It repeats the 52-61 aminocaid sequence of (Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys) of the Insulin-like Growth Factor 1 (IGF-1).

Supporting the active generation of new skin cells, Decapeptide-4 reduces and prevents fine lines and wrinkles according to the manufacturer's claim. It boosts both keratinocytes and fibroblast cell proliferation in just 72 hours. Applied topically, it increases collagen and elastin production, improving skin elasticity and firmness.

Decapeptide-4 is also used as an anabolic peptide in preparations for injections in fatty tissue. It blocks the production of new triglycerides and restructures subcutaneous adipose tissue.

In hair care applications, Decapeptide-4 activates the division and differentiation of hair papilla stem cells, stimulating the growth of strong, healthy hair. It is used in peptide cocktails to restore hair growth.
Synonyms
CG-IDP2
Somatomedin C Peptide
Changed

References

Characterization of Insulin-Like Growth Factor-I/Somatomedin-C Receptors on Human Keratinocyte Monolayers
Author(s):
, , , ,
DOI:
10.1111/1523-1747.ep12696645
Applications of the regenerative capacity of platelets in modern medicine
Author(s):
, , , , , ,
PMID:
34924312
DOI:
10.1016/j.cytogfr.2021.11.003
Somatomedin-C and platelet-derived growth factor stimulate human fibroblast replication
Author(s):
,
PMID:
7194347
DOI:
10.1002/jcp.1041060305