Functions
Hair growth stimulator
Regeneration booster
Firming
Anti-aging
FDA UNII
7G3XN5NND2
INCI name
Octapeptide-2
Identifier
CIG-1523
Origin
Synthetic
Octapeptide-2 is a synthetic peptide, a fragment of Thymosin β4, that strengthens hair and promotes its growth. It has the sequence Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln and is also known under the trade name Prohairlin-β4.
Boosting follicle stem cell development and activity, Octapeptide-2 promotes hair growth. In addition, it accelerates cell migration in hair follicles and inhibits apoptosis, reinforcing hair and imparting a healthy shine.
Moreover, Octapeptide-2 inhibits protease production, restoring hair growth. In addition, it stimulates the synthesis of collagen, elastin, and fibronectin by fibroblasts, accelerating wound healing, angiogenesis, and regenerative processes, and leaving an anti-aging effect on the skin.
Compared with native hair-boosting proteins, Prohairlin-beta4 is more stable and has a prolonged action. Octapeptide-2 is used in high-end hair growth-stimulating shampoos, masks, and serums.See also
Synonyms
Prohairlin-β4
Prohairlin-beta4
Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Changed
References
Biological activities of thymosin beta4 defined by active sites in short peptide sequences
PMID:
20179146
DOI:
10.1096/fj.09-142307
Thymosin beta 4 and a synthetic peptide containing its actin-binding domain promote dermal wound repair in db/db diabetic mice and in aged mice
PMID:
12581423
DOI:
10.1046/j.1524-475x.2003.11105.x
Distribution and biological activity ofβ-thymosins
DOI:
10.1007/BF00808118
