Oligopeptide-6 is a synthetic matrikine peptide that repeats a part of the sequence of Laminin-5 and mimics its action on skin cells. It interacts with integrins and receptors on the surfaces of skin cells, promoting their adhesion and migration.
Oligopeptide-6 has the sequence Arg-Asp-Phe-Thr-Lys-Ala-Thr-Asn-Ile-Arg-Leu-Arg-Phe-Leu-Arg, the C-terminus part of which corresponds to Heptapeptide-8 (Ile-Arg-Leu-Arg-Phe-Leu-Arg, also derived from Laminin-5). It is also known under the trade name Peptide Vinci 01™.
Promoting Integrins (proteins) gene expression and production, Oligopeptide-6 improves cellular adhesion. It boosts Laminin-5 production, recovering DEJ (Dermal-Epidermal Junction) integrity. Laminin-5 is located on the cell membrane and is a key molecule involved in adhesion; its deficiency is associated with the aging process in the skin.
In addition, Oligopeptide-6 enhances the synthesis of extracellular matrix (ECM) proteins and boosts regenerative processes, resulting in smoother, healthier, and rejuvenated skin. It is used as a repair and regeneration booster in many high-end anti-aging applications.
