Methyl Undecylenoyl Dipeptide-16, a derivative of Methyl Undecenoyl Leucinate. According to the manufacturer's claim, it interacts with Melanocortin 1 receptor (MC1R) and competes with alpha-MSH for binding. It has the sequence Und-Leu-Leu-O-Me and is known under the trade name DermaPep™ W220.
Methyl Undecylenoyl Dipeptide-16 prevents any further activation of melanogenic genes and reduces melanin production. In addition, it reduces UVB-induced inflammation, thereby providing a significant photoprotective effect.
The manufacturer's in vitro and in vivo studies show that Methyl Undecylenoyl Dipeptide-16 is far more effective than whitening ingredients such as arbutin. An in vivo clinical study demonstrated that it is a highly effective and safe agent for making the skin brighter, youthful, and radiant.
Dermatological tolerance standard testing has been performed on Methyl Undecylenoyl Dipeptide-16, which has shown no cytotoxicity, irritation, or sensitization reactions in healthy volunteers using an occlusive single-patch test.
