Zinc Hexapeptide-11

Functions
Anti-acne
Anti-inflammatory
Skin whitening agent
Firming
Smoothing
Hydrating
Anti-aging
Exfoliator
Skin conditioning
INCI name
Zinc Hexapeptide-11

Many eukaryotic microorganisms, like Saccharomyces cerevisiae, developed protective mechanisms in response to environmental damaging factors like UV exposure, temperature changes (excess heat or freezing), or oxidative agents like ozone. They produce protective peptides that promote proliferation and increase cell viability.

Hexapeptide-11 with sequence Phe-Val-Ala-Pro-Phe-Pro, known under the trade name Peptamide™ 6, is one of the peptides found in stressed yeast lysate extracts, which possesses extraordinary biological activity on the skin cells. It promotes regenerative processes, accelerates wound healing, and leaves an overall anti-aging effect.

Zinc Hexapeptide-11 is a metal-complexed cosmetic peptide. According to the manufacturer's claims, it is a multifunctional biologically active peptide that decreases proinflammatory TNF-α (Tumor Necrosis Factor-alpha) production and melanin synthesis. It also inhibits MMPs (Matrix metalloproteinases) via the PPAR (Peroxisome Proliferator-Activated Receptor) signaling pathway, lessening collagen degradation. In short, Zinc Hexapeptide-11 can leave anti-inflammatory (anti-acne), skin-whitening, and firming effects on the skin.

On the other hand, manufacturers claim that Zinc Hexapeptide-11 enhances hyaluronic acid and collagen production and improves KLKs (Kallikreins) activity. Kallikreins are proteases regulating natural desquamation; they break down proteins responsible for keratinocyte cohesion. So, Zinc Hexapeptide-11 improves skin hydration, elasticity, and renewal. It is frequently used with Hexapeptide-11 in a complex for a synergic potentiating effect.

 

 

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