Lactic Acid/Glycolic Acid Copolymer

Functions
Delivery vehicle
Liposome forming agent
Exfoliator
CAS Number(s)
34346-01-5
INCI name
Lactic Acid/Glycolic Acid Copolymer

Lactic Acid/Glycolic Acid Copolymer (PLGA) is a polymer consisting of Lactic and Glycolic acid units (monomers) specially designed to improve ingredient delivery systems, especially microspheres containing actives. Easily degradable in the skin with the presence of water, this AHA-based polymer breaks down, releasing active ingredients from microspheres in the deeper layers of the skin, thereby improving penetration levels and enhancing the overall effectiveness of the formula.

When combined with polyvinyl alcohol, the Lactic Acid/Glycolic Acid Copolymer forms more stable nanoparticles with reduced hydrophobicity, allowing for their incorporation into o/w emulsions with a wide range of oils and other ingredients. This technique is utilized in an advanced cosmetic active delivery system, featuring stability with a targeted and controlled release of active ingredients.

The monomers of Lactic Acid/Glycolic Acid Copolymer are common skincare ingredients that facilitate natural metabolism in skin cells. Thus, it is a perfect (safe and effective) delivery system with additional benefits, as released alpha-hydroxy acids help exfoliate dead and pigmented cells from the surface and improve water-binding ability, thereby optimally hydrating the skin.

PLGA is suitable for modern peptide complexes that have proven their effectiveness in anti-aging, skin whitening, and other targeted action preparations. The Food and Drug Administration (FDA) approved approach is widely used in high-end skincare products.
Synonyms
PLGA
Changed

References

Hybrid poly(lactic-co-glycolic acid) nanoparticles: design and delivery prospectives
Author(s):
, ,
PMID:
25277320
DOI:
10.1016/j.drudis.2014.09.018
Poly(lactic-co-glycolic acid) as a particulate emulsifier
Author(s):
, , , ,
PMID:
22440727
DOI:
10.1016/j.jcis.2012.02.058

Simplified explanation

Lactic Acid/Glycolic Acid Copolymer is a special ingredient made from two AHAs. It helps form a tiny microscopic container to carry the necessary ingredients deep into the skin. The container breaks down and releases these ingredients, allowing skincare products to work more effectively.

Even after decay, Lactic Acid/Glycolic Acid Copolymer becomes an AHA, which also helps remove dead skin cells and keeps skin hydrated. When mixed with another ingredient, polyvinyl alcohol, it becomes more stable and can be used in cosmetics containing oils.