PEG-100 Stearate

Functions
Surfactant
Solubilizer
Emulsifier
Emulsion stabilizer
Detergent
Delivery vehicle
Liposome forming agent
Gel Forming
CAS Number(s)
9004-99-3
FDA UNII
YD01N1999R
INCI name
Peg-100 Stearate
Identifier
CIG-465

PEG-100 Stearate is a product of poly-ethoxylation of stearic acid (18-carbon backbone fatty acid) that contains 100 moles of ethylene oxide (polymer part). The raw materials have mixed origins, namely, petrochemical and botanical. PEG-100 Stearate is a white to light brown solid with a negligibly specific fatty scent.

It is used in skin care preparations as a nonionic surfactant, solubilizer, or emulsifier (HLB value of 18.8) with good hydrophilic properties, enabling the production of stable emulsions containing lipophilic ingredients in water. PEG-100 Stearate can be used in delivery systems such as emulsified liposomes and solid lipid nanoparticles (SLNs).

PEG-100 Stearate enables the incorporation of salts and other electrolytes into emulsions and is widely used in skin care preparations for its stabilizing action. It is also often used with lower-HLB-value emulsifiers, such as Glyceryl Stearate, to form stable oil-in-water emulsions with a creamy consistency and a good sensory profile. Combined with Sorbitan Stearate, it enables gel-like products with improved viscoelastic properties.

PEG-100 Stearate is used in hand soaps, lotions, and creams. It can also serve as a solubilizer for perfumes, bath oils, and other aqueous-alcoholic preparations. It is also a viscosity builder and humectant for night creams and replenishing creams.
Synonyms
Polyethylene glycol 100 stearate
PEG 100-S
Changed

References

Development and characterization of topical formulation for maintenance therapy containing sorbitan monostearate with and without PEG-100-stearate
Author(s):
, ,
PMID:
39282719
DOI:
10.1111/ics.13023
PEG-stearate coated solid lipid nanoparticles as levothyroxine carriers for oral administration
Author(s):
,
DOI:
10.1007/s11051-014-2293-6
Statistical simplex centroid experimental design and formulation maps to predict the stability in cosmetic emulsions containing commercial emulsifiers
Author(s):
, , , , ,
DOI:
10.1002/jsde.12852
Unexpected skin barrier influence from nonionic emulsifiers
Author(s):
, ,
DOI:
10.1016/S0378-5173(99)00388-9
Re-Review Summary of PEG Stearates as Used in Cosmetics
Author(s):
, , , , , , , , , ,
DOI:
10.1177/10915818251359230