Carbomer

Functions
Emulsifier
Emulsion stabilizer
Thickener
Gel Forming
Viscosity controlling agent
Delivery vehicle
CAS Number(s)
9007-20-9
9003-01-4
76050-42-5
9062-04-8
9007-16-3
9007-17-4
INCI name
Carbomer
Origin
Synthetic

Carbomers are acrylic polymers used as cost-effective emulsifiers, stabilizers, or thickeners in skincare formulations. Its viscosity-building effect makes it suitable for use as a co-stabilizer in pharmaceutical and personal care applications. At the same time, its crystal-clear appearance also makes it ideal for use in hair gels.

Carbomer is a fine white acrylic powder used in hair gels, other gels, lotions, and creams. In addition, carbomer is tolerant of electrolytes and can be used in formulations with low pH values (AHA, DHA, whitening), as its efficacy range is 4-12.

It is also very resistant to high levels of ethanol or aminopropanol (up to 75 %), supporting the development of bactericide hand gels with a pleasant, smooth after-feel. The typical use level of carbomer is 0.1-0.5% depending o­n the type of formulation and final desired viscosity.

With sodium polyacrylate, the carbomer exhibits synergistic properties, a fresh, rapid-breaking effect balanced by a cushioning effect, and low-cost solutions for future gel, cream, and lotion formulations. In addition, it enhances skin penetration and can act as a delivery vehicle for active ingredients.

When combined with other polymers or neutralized with Ca2+, Carbomers can form nanoparticles for advanced delivery systems. Nanoparticles enhance the stability and penetration of active ingredients while enabling their controlled release.

Synonyms
2-Propenoic acid, polymer with 2,2-bis(hydroxymethyl)propane-1,3-diol 2-propenyl ether
Changed

References

Effects of carbomer 940 hydrogel on burn wounds: an in vitro and in vivo study
Author(s):
, , ,
PMID:
29316829
DOI:
10.1080/09546634.2018.1426823
Agarose Stearate-Carbomer940 as Stabilizer and Rheology Modifier for Surfactant-Free Cosmetic Formulations
Author(s):
, , , , ,
PMID:
34208474
DOI:
10.3390/md19060344
Quantitative Structure-Activity Relationship of Enhancers of Licochalcone A and Glabridin Release and Permeation Enhancement from Carbomer Hydrogel
Author(s):
, , , , , , , , , , ,
PMID:
35213995
DOI:
10.3390/pharmaceutics14020262
Nanoparticulate System Based on Calcium-Crosslinked Carbomer Retards Percutaneous Drug Permeation: New Insight Into Skin Barrier Functions
Author(s):
PMID:
36229583
DOI:
10.1007/s11095-022-03410-y
Therapeutic Effect of Liquiritin Carbomer Gel on Topical Glucocorticoid-Induced Skin Inflammation in Mice
Author(s):
, , , , ,
PMID:
39204346
DOI:
10.3390/pharmaceutics16081001