Palmitoyl sh-Tripeptide-2 Amide is a low molecular weight lipo-peptide derived from Tumor Necrosis Factor Receptor (TNFR; Tumor necrosis factor receptor superfamily member 1B) that inhibits TNF-α (Tumor Necrosis Factor-α; Tumor Necrosis Factor). It has the sequence Pal-His-Leu-Leu-NH2 and is known under the trade name Tenefrin™.
TNF-α, or Tumor Necrosis Factor, is a proinflammatory cytokine produced in the skin after UVB exposure. It is also involved in inflammatory processes in Psoriasis, and TNF-α antagonists are usually prescribed to those patients.
According to the manufacturer, Palmitoyl sh-Tripeptide-2 Amide acts as an antagonist of TNF-α, an inflammatory factor, and, when applied topically, soothes irritated skin and leaves a noticeable anti-inflammatory effect.
Decapeptide-19 is a synthetic peptide with the sequence Ala-Cys-Asp-Gly-Arg-Thr-Gln-Ala-Leu-Cys that inhibits the specific biological activity of TNF-α cytokine and exhibits anti-inflammatory and hair growth-promoting properties. It is known under the trade name CG-Elima.
Palmitoyl sh-Tripeptide-4 Amide is a low molecular weight lipo-peptide (316.3 Da) derived from CD99, a cell membrane antigen-like multifunctional protein that is expressed in human cells.
NF-kB is a transcription factor involved in the proinflammatory responses causing skin aging and inflammation. Acetyl Tripeptide-74 Amide is a lipo-peptide that inhibits NF-kB activity and acts as a skin soothing, anti-inflammatory, and anti-photo-aging agent.
sh-Polypeptide-6 is a synthetic recombinant single-chain peptide, an analog of human Interleukin 10 (IL-10). Interleukin 10 is an anti-inflammatory cytokine that regulates the immune response and antibody production.
Palmitoyl sh-Tetrapeptide-2 Amide is a lipo-peptide that inhibits Interleukin-1R, an inflammatory cytokine receptor, soothing skin irritation and acting as an anti-inflammatory agent.
Capryloyl Pentapeptide-26 is a synthetic lipopeptide derived from neurotransmitter Substance P (SP). Its amino acid sequence (Pentapeptide-26) corresponds to the C-terminus of SP, which has the sequence Phe-Phe-Gly-Leu-Met and is known in the scientific literature as SP7-11.
sh-Pentapeptide-1 (former designation: Pentapeptide-1) is a synthetic recombinant peptide derived from thymopoietin, a human hormone with immunomodulating properties.
Acetyl Tetrapeptide-40 is a synthetic peptide that decreases the release of pro-inflammatory interleukins (IL-6 and IL-8), fighting against skin redness, erythema, and telangiectasias. It is known under the trade name Telangyn™, and the sequence is Acetyl-Ala-Thr-Asn-Thr.
sh-Polypeptide-40 is a synthetic recombinant human placental lactogen (hPL) hormone analog peptide composed of 192 amino acids. hPL is also known as human chorionic somatomammotropin (hCS) or human chorionic somatotropin.
sh-Oligopeptide-85 SP is a synthetic human recombinant peptide that has the sequence Gly-Phe-Ile-Asn-Leu-Asp-Lys-Pro-Ser-Asn-Pro corresponding to the part of the TruB domain of the human Dyskerin (89-100) protein.
Tetrapeptide-30 is a synthetic peptide PKEK (sequence: Pro-Lys-Glu-Lys) that contains a KEK (Lys-Glu-Lys) motif found in antimicrobial polypeptide cathelicidin which can reduce post-inflammatory or UV-induced hyperpigmentation.
