Palmitoyl sh-Tripeptide-2 Amide is a low molecular weight lipo-peptide derived from Tumor Necrosis Factor Receptor (TNFR) that inhibits TNF-α ( tumor-necrosis factor-α). It is known under the trade name Tenefrin™.
Inhibiting TNF-α ( tumor-necrosis factor-α) an inflammatory factor, Palmitoyl sh-Tripeptide-2 Amide soothes irritated skin acting as an anti-inflammatory agent.
Functions
Soothing
Anti-inflammatory
Humectant
Protective
Synonyms
Tenefrin™
Related ingredients
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Sensitive skin is often defined by a propensity to sensory responses such as stinging, itching, burning, or visible reactions, such as erythema, papules or vesicles, wheal and flare responses, dryness, scaling, and desquamation, in response to external stimuli.
The skin is facing many kinds of stress, such as aging, mycobacterium and virus attack, UV and infrared light, and recently issued environmental stress, such as pollen, PM2.5, and PM10, including its harmful components polycyclic aromatic hydrocarbons (PAHs) and heavy metals.
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sh-Polypeptide-12 is a synthetic recombinant single-chain peptide, an analog of human Interleukin 4 (IL-4), that acts as an antihistamine or immune-suppressor agent to reduce scratching by inhibiting the autoimmune response.