3-Laurylglyceryl Ascorbate

Functions
Barrier enhancer
Antioxidant
Humectant
Skin whitening agent
Firming
Anti-aging
CAS Number(s)
1120360-38-4
INCI name
3-Laurylglyceryl Ascorbate

3-Laurylglyceryl Ascorbate is a stable vitamin C derivative. It is a modified 3-Glyceryl Ascorbate with an attached alkyl (Lauryl or dodecyloxy; C12) group to the glyceryl group. It is also known under the trade name Amitose 3LGA.

Besides its exceptional skin-moisturizing and melanin-inhibiting effects typical of vitamin C derivatives, 3-Laurylglyceryl Ascorbate activates ceramide production and enhances the intracellular antioxidant system, replenishing and reinforcing skin's barrier function and protecting dermal cells from oxidative stress.

3-Laurylglyceryl Ascorbate stimulates antioxidant enzymes production Heme Oxygenase-1 (HO-1) and NAD(P)H Quinone Oxidoreductase-1 (NQO1). Moreover, novel studies have shown that the topical application of 3-Laurylglyceryl Ascorbate regulates Interleukin-1α, NGF (Nerve Growth Factor), and MMP-9 (Matrix Metalloproteinase-9), thereby preventing the development of sensitive skin in dry skin conditions.

Incorporated into skincare applications, 3-Laurylglyceryl Ascorbate provides multiple beneficial effects, including skin-whitening, antioxidant, anti-aging, barrier-enhancing, and firming.
Synonyms
Amitose 3LGA
VC-3LG
3-O-Laurylglyceryl Ascorbate
Changed

References

The Relationship between the Molecular Structures of Alkyl Glyceryl-Ascorbate Derivatives and Their Inhibitory Effects on Melanogenesis
Author(s):
, , , ,
DOI:
10.5107/sccj.49.32
3-O-Laurylglyceryl ascorbate reinforces skin barrier function through not only the reduction of oxidative stress but also the activation of ceramide synthesis
Author(s):
, , , , ,
PMID:
27261166
DOI:
10.1111/ics.12347
3-O-Laurylglyceryl ascorbate activates the intracellular antioxidant system through the contribution of PPAR-γ and Nrf2
Author(s):
, , , ,
PMID:
26976686
DOI:
10.1016/j.jdermsci.2016.03.002
3-O-Laurylglyceryl ascorbate improves the development of sensitive skin through the reduction of oxidative stress
Author(s):
, , , , ,
PMID:
30698879
DOI:
10.1111/exd.13820