sh-Pentapeptide-5 is a synthetic recombinant peptide, an analog of human Leu-Enkephalin that mimics endorphin action and leaves a Botox-like effect. This opioid peptide effectively reduces the appearance of expression lines and deep wrinkles, exposing smoother, younger-looking, and healthier skin.
In addition to its Botox-like action, sh-Pentapeptide-5 also mimics the Epidermal Growth Factor (EGF-like effect), promoting skin's regeneration and repair processes. It revitalizes the skin, improving texture, resilience, and barrier function.
When combined with Potassium Glutathione Isomerized Linoleate, sh-Pentapeptide-5 forms a peptide complex called Peptilift to improve delivery and provide additional benefits such as hydration, detoxification, and antioxidant action. This peptide-based complex is used in many formulations for lifting, smoothing, and anti-aging.
Synonyms
Peptilift
Leucine Enkephalin
Leu-Enkephalin
Changed
References
A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neurones
Author(s):
Jankowska E, Schomburg ED
PMID:
9706000
DOI:
10.1111/j.1469-7793.1998.513bk.x
Biomimetic endorphin for wrinkle lifting in a daily cosmetic remedy
RonaCare® Cyclopeptid-5 rapidly gives the skin a fresher and more youthful appearance. The peptide replicates the natural processes of skin communication and repair.
sh-Oligopeptide-4 is a synthetic recombinant Thymosin-β4 peptide that helps strengthen hair while stimulating hair follicles to produce healthier hair.
sh-Polypeptide-19 (former rh-Oligopeptide-3 and rh-Polypeptide-19) is a synthetic single-chain recombinant peptide, an analog of human TGF-α (Transforming Growth Factor-α).
Acetyl Octapeptide-17 Amide is a synthetic peptide that mimics a functional part of EGF (Epidermal Growth Factor) with the sequence Ac-Met-Leu-Lys-Glu-Trp-Glu-Leu-Arg-NH2.
Oligopeptide-55 is a synthetic 12 amino acid long peptide that boosts keratinocytes and fibroblasts proliferation and collagen and elastin production improving skin elasticity and resilience.
Pentapeptide-18 acts similar to natural enkephalins (proven in vitro study): it couples to the enkephalin receptor on the outside of the nerve cells, relaxing expression muscles and smoothing wrinkles.
