sh-Pentapeptide-5 is a synthetic recombinant peptide, an analog of human Leu-Enkephalin that mimics endorphin action and leaves a Botox-like effect. This opioid peptide effectively reduces the appearance of expression lines and deep wrinkles, exposing smoother, younger-looking, and healthier skin.
In addition to its Botox-like action, sh-Pentapeptide-5 also mimics the Epidermal Growth Factor (EGF-like effect), promoting skin's regeneration and repair processes. It revitalizes the skin, improving texture, resilience, and barrier function.
When combined with Potassium Glutathione Isomerized Linoleate, sh-Pentapeptide-5 forms a peptide complex called Peptilift to improve delivery and provide additional benefits such as hydration, detoxification, and antioxidant action. This peptide-based complex is used in many formulations for lifting, smoothing, and anti-aging.
Synonyms
Peptilift
Leucine Enkephalin
Leu-Enkephalin
Changed
References
A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neurones
Author(s):
Jankowska E, Schomburg ED
PMID:
9706000
DOI:
10.1111/j.1469-7793.1998.513bk.x
Biomimetic endorphin for wrinkle lifting in a daily cosmetic remedy
sh-Polypeptide-19 (former rh-Oligopeptide-3 and rh-Polypeptide-19) is a synthetic single-chain recombinant peptide, an analog of human TGF-α (Transforming Growth Factor-α). TGF-α boosts the generation and migration of keratinocytes, accelerates wound healing, and improves skin tone.
Acetyl Octapeptide-17 Amide is a synthetic peptide that mimics a functional part of EGF (Epidermal Growth Factor) with the sequence Ac-Met-Leu-Lys-Glu-Trp-Glu-Leu-Arg-NH2. It is known under the trade names Dermacurin and Mini EGF.
Pentapeptide-48 is a synthetic peptide with the sequence Thr-Arg-Ser-Glu-Leu that repeats the active part of the Royalactin protein. Royalactin is a protein found in royal jelly and it is responsible for the epigenetic changes in the larvae's DNA, creating the queen bee phenotype.
Oligopeptide-55 is a synthetic 12 amino acid long peptide that boosts keratinocytes and fibroblasts proliferation and collagen and elastin production improving skin elasticity and resilience. This peptide is also known under the trade name CG-Collagrin.
Pentapeptide-18 acts similar to natural enkephalins (proven in vitro study): it couples to the enkephalin receptor on the outside of the nerve cells, relaxing expression muscles and smoothing wrinkles.
sh-Polypeptide-10 is a synthetic recombinant single-chain peptide, an analog of human Fibroblast Growth Factor 10 (FGF10) that is involved in normal skin growth, regeneration, and wound repair.
sh-Polypeptide-93 is a synthetic recombinant human connective tissue growth factor (CTGF) analog peptide composed of 324 amino acids. It mimics the Insulin-like Growth Factor (IGF)-binding domain of CTGF and regulates the expression of genes responsible for collagen production in fibroblasts.
Palmitoyl sh-Tripeptide-1 Amide is a low molecular weight synthetic recombinant lipo-peptide derived from FGF-1 (Fibroblast Growth Factor-1; sequence part 99-101) that is involved in various cellular processes, including angiogenesis, keratinocyte organization, and wound healing.
sr-Clostridium Botulinum Polypeptide-1 is a protein toxin (1296 amino acids in length) derived from the fermentation of Clostridium botulinum bacteria, was historically used as a medical treatment for localized movement disorders such as blepharospasm (an involuntary movement of the eyelid)
