sh-Pentapeptide-5 is a synthetic recombinant peptide, an analog of human Leu-Enkephalin that mimics endorphin action and leaves a Botox-like effect. This opioid peptide effectively reduces the appearance of expression lines and deep wrinkles, exposing smoother, younger-looking, and healthier skin.
In addition to its Botox-like action, sh-Pentapeptide-5 also mimics the Epidermal Growth Factor (EGF-like effect), promoting skin's regeneration and repair processes. It revitalizes the skin, improving texture, resilience, and barrier function.
When combined with Potassium Glutathione Isomerized Linoleate, sh-Pentapeptide-5 forms a peptide complex called Peptilift to improve delivery and provide additional benefits such as hydration, detoxification, and antioxidant action. This peptide-based complex is used in many formulations for lifting, smoothing, and anti-aging.
Synonyms
Peptilift
Leucine Enkephalin
Leu-Enkephalin
Changed
References
A leu-enkephalin depresses transmission from muscle and skin non-nociceptors to first-order feline spinal neurones
Author(s):
Jankowska E, Schomburg ED
PMID:
9706000
DOI:
10.1111/j.1469-7793.1998.513bk.x
Biomimetic endorphin for wrinkle lifting in a daily cosmetic remedy
Oligopeptide-55 is a synthetic 12 amino acid long peptide that boosts keratinocytes and fibroblasts proliferation and collagen and elastin production improving skin elasticity and resilience.
Pentapeptide-18 acts similar to natural enkephalins (proven in vitro study): it couples to the enkephalin receptor on the outside of the nerve cells, relaxing expression muscles and smoothing wrinkles.
sh-Polypeptide-10 is a synthetic recombinant single-chain peptide, an analog of human Fibroblast Growth Factor 10 (FGF10) that is involved in normal skin growth, regeneration, and wound repair.
Palmitoyl sh-Tripeptide-1 Amide is a low molecular weight synthetic recombinant lipo-peptide derived from FGF-1 (Fibroblast Growth Factor-1; sequence part 99-101) that is involved in various cellular processes, including angiogenesis, kera
sr-Clostridium Botulinum Polypeptide-1 is a protein toxin (1296 amino acids in length) derived from the fermentation of Clostridium botulinum bacteria, was historically used as a medical treatment for localized movement disorders such
Decapeptide-4 is a synthetic peptide known under the trade name CG-IDP2 that mimics the Somatomedin C (IGF-1) growth factor involved in normal skin growth, healing, and wound repair.
Oligopeptide-72 is a synthetic biomimetic peptide that boosts the proliferation and morphological changes of dermal fibroblasts, exposing lifted, healthy, and youthful skin appearance.
sh-Polypeptide-31 is a synthetic recombinant peptide that mimics human Insulin-like Growth Factor-2 (IGF-2). The old designation was rh-Polypeptide-31 (rh- prefix means recombinant human).
sh-Oligopeptide-1 is a synthetic recombinant analog of human polypeptide EGF (Epidermal Growth Factor), which contains 53 amino acids with the sequence NSDSECPLSHDGYCLHDGV
Bio-Placenta is a complex composed of synthetic growth factors (mimicking peptide placental growth factors), vitamins, amino acid derivatives, and hyaluronic acid encapsulated in Lecithin nanoparticles that simulate dermal cell growth and
Hexapeptide-33 is a biologically active peptide with the sequence Ser-Phe-Lys-Leu-Arg-Tyr-NH2 (SFKLRY) that stimulates blood vessel formation, known under the trade name W3 peptide.