Dextrin

Functions
Binder
Filler
Thickener
Absorber
Bulking
Viscosity controlling agent
Gel Forming
Delivery vehicle
CAS Number(s)
9004-53-9
EINECS number(s)
232-675-4
FDA UNII
2NX48Z0A9G
INCI name
Dextrin
Identifier
CIG-1300

Dextrin is a general term for degraded starch polysaccharides in which the amylose and amylopectin present in the original starch have been partially hydrolyzed at the 1,4αD and 1,6αD linkages. It is a white-to-tan powder that can be used in a variety of cosmetic powder applications but shows exceptional performance in soap bar processing.

The starch helps structure and harden the bar. At the same time, Dextrin reduces tack, helping the bars release easily from the molds after extrusion. The incorporation of Dextrin can improve manufacturing efficiency in soap production. In addition, it is a cost-effective filler, sensory modifier, or delivery vehicle for active ingredients used in many personal care applications.

Thanks to its excellent skin affinity, Dextrin is used in many cosmetic complexes for encapsulation, conjugation, or gel formation. Avobenzone, one of the most popular UV filters, coated with this polysaccharide, showed improved UV protection and reduced skin penetration.

Several anti-aging and antibacterial peptides conjugated with Dextrin also showed better performance. For example, the conjugate with sh-Oligopeptide-1 (rhEFG) exhibited increased resistance to proteolytic enzymes and other factors and sustained bioactivity, demonstrating good results in fibroblast proliferation, wound-healing acceleration, and anti-aging effects.

Dextrin is a safe, well-studied, and multifunctional ingredient for personal care applications. It is ecologically friendly, rapidely biodegradable, and safe for aquatic organisms.

See also
Synonyms
Icodextrin
Dextrin
Changed

References

Avobenzone encapsulated in modified dextrin for improved UV protection and reduced skin penetration
Author(s):
, , ,
DOI:
10.1515/chempap-2016-0021
Bioresponsive Dextrin−rhEGF Conjugates: In Vitro Evaluation in Models Relevant to Its Proposed Use as a Treatment for Chronic Wounds
Author(s):
, , , , ,
DOI:
10.1021/mp9002656
The effect of dextrin–rhEGF on the healing of full-thickness, excisional wounds in the (db/db) diabetic mouse
Author(s):
, , , , ,
DOI:
10.1016/j.jconrel.2011.03.016
Improved burn wound healing by the antimicrobial peptide LLKKK18 released from conjugates with dextrin embedded in a carbopol gel
Author(s):
, , , , , ,
DOI:
10.1016/j.actbio.2015.07.043
Dextrin: A Platform for the Development of Drug Delivery Systems
Author(s):
Journal:
Universidade do Minho (Portugal) ProQuest Dissertations & Theses,  2022. 30650643.
Nutraceutical Concepts and Dextrin-Based Delivery Systems
Author(s):
, , , , , , ,
DOI:
10.3390/ijms23084102
Characterization of dextrin‐based hydrogels: Rheology, biocompatibility, and degradation
Author(s):
, , ,
DOI:
10.1002/jbm.a.32553
Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics
Author(s):
, , , , , , , , , , ,
PMID:
27383198
DOI:
10.1177/1091581816651606