Biosaccharide gum-2 is a biotechnological polysaccharide obtained by bacterial fermentation of plant substrates that forms a branched structure and a sequence of sugars, rich in rhamnose. It acts as a trap, binding to membrane receptors on attacked keratinocytes and modulating the inflammatory cascade.
Our organism is controlled by communication mechanisms that maintain physiological balance. This communication is a dynamic relationship between transmitter and receiver structures, mediated by messages carried through a specific channel. The skin concentrates many cell-to-cell messages through mediators. Aging compromises skin cell communication.
Keratinocytes are part of the first line of defense in the cutaneous immune system; they synthesize several pro-inflammatory mediators, such as cytokines, that are released after activation by different stimuli. The primary cytokines IL-1α, IL-1-β, and TNF-α trigger skin inflammation through interaction with specific keratinocyte receptors. In addition to modulating inflammation, they also regulate cell proliferation and differentiation.
Consequently, Biosaccharide gum-2 helps prevent accelerated aging caused not only by specific agents but also by UV radiation, pollution, and chemical exposure, among others. Another important action is stimulating the release of β-endorphins, known as pleasure molecules, combining protection with well-being. Some researchers also mention its antifungal properties.In short, Biosaccharide gum-2 is a desensitizing agent with a specific fixation ability on keratinocyte receptors. It slows down the aging process and stimulates the synthesis of β-endorphins. By inhibiting the activity of PLA2 (Phospholipase A2) and decreasing the release of PGE2 (Prostaglandin E2), Biosaccharide gum-2 reduces the skin inflammatory process, including UV- and retinoid-induced irritation. It is a recommended ingredient for oily skin and baby care products.
