Authored by: Arthur Ghochikyan, M.D.
Functions
Antioxidant
Anti-aging
Anti-inflammatory
Smoothing
Moisturizer
Analgetic
Antibacterial
Emollient
INCI nameCannabis Sativa Seed Oil
Cannabis Sativa Seed Oil is a naturally rich hemp seed oil containing polyunsaturated fatty acids (90%) and essential fatty acids (75%). It offers an excellent balance of essential fatty acids and contains polyphenolic compounds, particularly flavonoids with noticeable antioxidant activity.
According to The Lipid Handbook, hemp seed contains 30–35% oil with an iodine value of 140–175. The predominant fatty acids are 18:1 (12%), 18:2 (55%), and 18:3 (25%). The oil is derived from the industrial hemp variety and possesses antimicrobial, soothing, and skin-moisturizing properties.
Cannabis sativa seed oil exhibits anti-inflammatory, skin-regenerating, and revitalizing properties. It also has analgesic properties and is used in specialized applications to relieve pain through topical application. It is entirely safe and non-toxic for the consumer when incorporated into personal care applications. It is permitted for culinary use and is widely used for edible purposes in Asia.
Naturally poor in Delta-9 Tetrahydrocannabinol eliminated during the extraction process, Cannabis Sativa Seed Oil's Delta-9 THC content is less than 0,0002%, as proven by chromatography analysis associated with mass spectrometry. The oil is obtained mainly by expelling and is used for similar purposes to linseed oil.
Rich in essential fatty acids and powerful antioxidants, Cannabis Sativa Seed Oil offers anti-aging benefits and improves skin smoothness, moisturization, and elasticity. Thanks to its Cannabidiolic acid content, it is effective against Gram+ and Gram- bacteria and against bacterial biofilm formation. In addition, it regulates the release of proinflammatory cytokines, decreasing the inflammatory response induced by bacterial infection.
With a light, non-greasy texture, Cannabis Sativa Seed Oil has excellent skin permeation and high penetration, making it frequently used in moisturizing creams and lotions. Besides skin care applications, it is also used in hair and sun care products, and decorative cosmetics.
References
Assessment of Moroccan Cannabis Sativa Seed Oil: Chemical Analysis and Evaluation of Antioxidant, Toxicological, and Antinociceptive Effects
Author(s):
Raoui K, Kabdy H, Ettitaou A, Aitbaba A, Baslam A, Benrazzouk K, Ait Laaradia M, Laaradraoui J, Oufquir S, Elyazouli L, Aboufatima R, Garzoli S, Chait A
DOI:
10.1002/cbdv.202400591
Effect of Topical Hemp (Cannabis sativa L.) Seed Oil on Knee Osteoarthritis: A Randomized Double-Blind Controlled Trial
Author(s):
Abbasifard M, Moosavi Z, Azimi M, Kamiab Z, Bazmandegan G, Madahian A, Raeiszadeh M
DOI:
10.1016/j.pmn.2024.08.001
The seed of industrial hemp (Cannabis sativa L.): Nutritional Quality and Potential Functionality for Human Health and Nutrition
Author(s):
Farinon B, Molinari R, Costantini L, Merendino N
Polyphenolic Compounds and Antioxidant Activity of Cold-Pressed Seed Oil from Finola Cultivar of Cannabis sativa L
Author(s):
Smeriglio A, Galati EM, Monforte MT, Lanuzza F, D'Angelo V, Circosta C
Polyphenolic Compounds and Antioxidant Activity of Cold-Pressed Seed Oil from Finola Cultivar of Cannabis sativa L
Author(s):
Smeriglio A, Galati EM, Monforte MT, Lanuzza F, D'Angelo V, Circosta C
In vitro antibacterial activity of hemp (Cannabis sativa L.) extract seed oil against multidrug resistant bacterial pathogens in small animal veterinary dermatology
Author(s):
Toppi V, Pirolo M, Rampacci E, Scattini G, Musa L, Della Rocca G, Di Salvo A, De Benedetti M, Guardabassi L, Proietti PC
DOI:
10.1016/j.tvjl.2025.106392
Cannabidiolic acid in Hemp Seed Oil Table Spoon and Beyond
Author(s):
Nigro E, Pecoraro MT, Formato M, Piccolella S, Ragucci S, Mallardo M, Russo R, Di Maro A, Daniele A, Pacifico S
DOI:
10.3390/molecules27082566
Potential oil yield, fatty acid composition, and oxidation stability of the hempseed oil from four Cannabis sativa L. cultivars
Author(s):
Da Porto C, Decorti D, Natolino A
DOI:
10.3109/19390211.2014.887601