Glyceryl Caprylate

Functions
Emollient
Emulsifier
Preservative booster
Preservative
Anti-acne
Penetration enhancer
CAS Number(s)
26402-26-6
EINECS number(s)
247-668-1
FDA UNII
TM2TZD4G4A
INCI name
Glyceryl Caprylate
Identifier
CIG-765

Glyceryl Caprylate is a monoglyceride, a monoester of caprylic acid with glycerin. Monoglycerides exhibit antimicrobial properties and are widely used as preservative busters in personal care formulations, providing additional benefits.

EcoCertified Glyceryl Caprylate is vegetable origin, non-petrochemical; natural fatty acids from pure, renewable resources provide broad-spectrum protection against bacteria, yeast, and mold. It also exhibits natural emollient properties and provides additional refatting and moisturization.

Studies have shown that the antimicrobial efficacy of glyceryl caprylate depends on the formulation pH; under acidic conditions, it is more active against mold and bacteria, suggesting it as a potential acne treatment and preservative for cosmetic applications.

Glyceryl Monocaprylate has also been tested as a premiation enhancer for pharmaceutical and cosmetic active ingredients and has shown promising results, improving absorption and penetration rates. It is a safe and effective ingredient for topical personal care applications; however, there are reports of skin sensitization and allergic reactions with subclinical manifestations.
Synonyms
Glyceryl Monocaprylate
Changed

References

A study on the antimicrobial effect of glyceryl caprylate in cosmetics
Author(s):
, , ,
Journal:
Journal of the Society of Cosmetic Scientists of Korea (2007;33(1):47-52)
A new alternative to cosmetics preservation and the effect of the particle size of the emulsion droplets on preservation efficacy
Author(s):
, , ,
DOI:
10.1111/ics.12317
Sensory mapping for common special esters in cream products
Author(s):
,
Journal:
The Online Journal of Science and Technology-October (2020;10(4))
Effect of Permeation Enhancers on the in Vitro Percutaneous Absorption of Pentazocine1
Author(s):
, , , , ,
Journal:
Biological and Pharmaceutical Bulletin (2007;30(7):1350-3)
Final report of the amended safety assessment of Glyceryl Laurate, Glyceryl Laurate SE, Glyceryl Laurate/Oleate, Glyceryl Adipate, Glyceryl Alginate, Glyceryl Arachidate, Glyceryl Arachidonate, Glyceryl Behenate, Glyceryl Caprate, Glyceryl Caprylate...
Author(s):
PMID:
15513825
DOI:
10.1080/10915810490499064
Glyceryl (mono)caprylate - a new contact allergen
Author(s):
, , , , , ,
PMID:
24215529
DOI:
10.1111/cod.12135