Diazolidinyl urea is an Allantoin derivative, a highly effective, broad-spectrum antibacterial preservative with excellent activity against Pseudomonas species. It is non-irritating to the eyes, skin, and mucous membranes at use levels. It is also known under the trade name Germall II.
Diazolidinyl urea acts as a formaldehyde releaser. It is highly water-soluble, retaining its activity in the presence of proteins, nonionic surfactants, and most other common ingredients used in personal care formulations and hand sanitizers. It may be added directly to aqueous systems without heating.
In a hot process, Diazolidinyl urea should be introduced during the cooling stage, below 60°C, and recommended below 40°C. Because it is hygroscopic, it should be stored in tightly sealed containers when not in use.
Diazolidinyl urea is a well-studied and widely used preservative. However, due to its formaldehyde-releasing mechanism, some researchers consider it a potential carcinogen and a genotoxic agent. There are many reports of sensitization, including contact dermatitis and other allergic reactions.
Hexamidine Diisethionate is a water-soluble antimicrobial cationic polyvalent preservative with a wide spectrum of protection against bacteria, fungi, and yeasts.
Methylparaben is a methyl ester of p-hydroxybenzoic acid, a widely used broad-spectrum preservative used in personal care products, pharmaceuticals, and some foods.
DMDM Hydantoin or Dimethylol dimethyl Hydantoin (DMDMH) is a derivative of formaldehyde and dimethyl hydantoin. It was designed as an odorless alternative to formaldehyde for permanent-pressed fabrics.
Optiphen ND is a complete liquid preservative complex containing no halo-organic components, formaldehyde, or formaldehyde releasers and is paraben-free.
Propylparaben is a propyl ester of p-hydroxybenzoic acid, a widely used broad-spectrum preservative used in personal care products, pharmaceuticals, and some foods.
Benzyl alcohol is a colorless liquid with a mild pleasant aromatic odor; it is a natural constituent of various essential oils, including jasmine, hyacinth, and ylang-ylang.
Imidazolidinyl Urea is a cosmetic preservative that is very active against Gram-negative, including Pseudomonas aeruginosa and positive bacteria. It has no activity against fungi and is synergistic with parabens.
