In the skincare industry Aesculin used in formulations for eye and foot care to treat under-eye bags and spider veins. It tones vessels, increases skin micro-circulation, and decongest the micro-vein network decreasing dark rings and bags under the eyes.
Microcirculation enhancer
Respiration is the process by which the cells of an organ, in this case skin, utilize oxygen and nutrients needed for efficient metabolism and health. Furthermore, respiration also includes the process by which an organ eliminates carbon dioxide and toxic elements before adverse reactions and damage occurs.
Blood circulation provides two-way transport for oxygen, carbon dioxide, nutrients, and metabolic products. In organs, the direct exchange of those compounds occurs in microvessels where blood flow is relatively slower, and circulation is conventionally called microcirculation.
As intrinsic damage (aging) and extrinsic damage (UV, pollution, etc.) become apparent in our appearance, the skin's blood vessels become impaired in their ability to function correctly. The subsequent decrease in blood flow also creates a consequential reduction in metabolism due to the decline in the delivery of oxygen and nutrients.
Microcirculation enhancers are ingredients that increase blood flow and respiration to the skin. Some act directly on vessels, while others help preserve the integrity of microvessels, indirectly improving blood flow and organs' respiration.Certain ingredients (such as methyl nicotinate) and plant derivatives (such as capsaicin) are well-documented for their direct effect on enhancing blood flow. Phytonadione (vitamin K), Esculin, and other vessel-toning ingredients act indirectly, maintaining microvessel integrity and permeation and leaving decongesting, microcirculation-enhancing, and anti-spider vein effects.
Traditionally Horsetail (Equisetum arvense) extract has been used for the treatment of inflammatory conditions in Europe. Novel experimental findings showed that Equisetum arvense has a modulatory effect on T-leucocytes that producing mediators of inflammation. It provides an anti-inflammatory effect, soothing, smoothing edema, and eliminating irritation of the skin.
Phytonadione is a plant-based, fat-soluble Vitamin K1. It is absorbed through plant-based foods (green vegetables, e.g., cabbage, lettuce, and lamb's lettuce) in the human body. Vitamin K is responsible for various body functions and is found in almost all cells.