Boswellia Serrata Extract is a lipophilic extract of Boswellia gum, which is used in Ayurvedic medicine to treat chronic inflammatory diseases and osteoarthritis. It is rich in triterpenoids, including acetylketo-Boswellic and keto-Boswellic acids, and is recommended for anti-aging products and sensitive skin.
Modern studies showed that Boswellia serrata extract potently inhibits leukotriene production by blocking 5-lipoxygenase, making it useful for soothing acute and chronic irritations. Another study suggested that it can be used as an antibiofilm agent against Candida species.
Combined with Curcumin, Boswellia Serrata Extract showed promising results in oral care applications for the treatment of stomatitis of different origins. Thanks to its potent anti-inflammatory properties, it was also used to treat erythema and other skin symptoms after radiotherapy, thereby reducing the need for the corticosteroids traditionally used to alleviate those adverse effects.
Boswellia Serrata Extract can also be used for firming (by inhibiting elastase), regulating desquamation, and improving the skin barrier (by inhibiting Cathepsin D). The usage level is 0.1-0.2%. Safety and toxicological tests showed that this ingredient is non-toxic, non-mutagenic, and non-clastogenic. It is safe for skin, scalp, and oral care preparations in recommended concentrations.
Boswellia serrata, a potential antiinflammatory agent: an overview
Author(s):
Siddiqui MZ
PMID:
22457547
DOI:
10.4103/0250-474X.93507
Boswellia serrata Extract as an Antibiofilm Agent against Candida spp
Author(s):
Jaroš P, Vrublevskaya M, Lokočová K, Michailidu J, Kolouchová I, Demnerová K
PMID:
35056620
DOI:
10.3390/microorganisms10010171
Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data
Author(s):
Abdel-Tawab M, Werz O, Schubert-Zsilavecz M
PMID:
21553931
DOI:
10.2165/11586800-000000000-00000
Development and characterization of bacterial nanocellulose loaded with Boswellia serrata extract containing nanoemulsions as natural dressing for skin diseases
Author(s):
Karl B, Alkhatib Y, Beekmann U, Bellmann T, Blume G, Steiniger F, Thamm J, Werz O, Kralisch D, Fischer D
PMID:
32693288
DOI:
10.1016/j.ijpharm.2020.119635
Toxicological Assessment of a Standardized Boswellia serrata Gum Resin Extract
Author(s):
Alluri VK, Dodda S, Kilari EK, Golakoti T, Sengupta K
PMID:
31234670
DOI:
10.1177/1091581819858069
Curcumin and Boswellia serrata gum resin extract inhibit chikungunya and vesicular stomatitis virus infections in vitro
Author(s):
von Rhein C, Weidner T, Henß L, Martin J, Weber C, Sliva K, Schnierle BS
PMID:
26611396
DOI:
10.1016/j.antiviral.2015.11.007
Safety and Toxicological Evaluation of a Novel, Standardized 3-O-Acetyl-11-keto-beta-Boswellic Acid (AKBA)-Enriched Boswellia serrata Extract (5-Loxin(R))
Author(s):
Lalithakumari K, Krishnaraju AV, Sengupta K, Subbaraju GV, Chatterjee A
PMID:
20021046
DOI:
10.1080/15376520600620232
Clinical evaluation of safety and efficacy of Boswellia-based cream for prevention of adjuvant radiotherapy skin damage in mammary carcinoma: a randomized placebo controlled trial
Author(s):
Togni S, Maramaldi G, Bonetta A, Giacomelli L, Di Pierro F
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