Functions
Carrier
Perfuming
Emollient
Solubilizer
Liposome forming agent
Delivery vehicle
CAS Number(s)
538-23-8
EINECS number(s)
208-686-5
FDA UNII
6P92858988
INCI name
Tricaprylin
Identifier
CIG-2515
Tricaprylin (also known as glycerol tricaprylate; its former designation was Tricaprylate) is a triglyceride ester of caprylic acid and glycerine. Refined and deodorized, it is a clear, bland-smelling liquid that is miscible with most organic solvents, including pure ethanol.
Tricaprylin has excellent stability, low irritation, and a bland taste and odor. It is used in pharmaceuticals, perfume, and personal care products as an emollient, solubilizer, and carrier. It appears in lotions, creams, and decorative cosmetics.
In advanced complexes, Tricaprylin is used as a liposome-forming agent that encapsulates unstable substances, such as Vitamin C, improving the ingredient's penetration, permeability, and stability for topical application.
Synonyms
Tricaprilin
Tricaprylate
Glycerol Tricaprylate
Changed
References
Design of Novel Tricaprylin-Incorporated Multi-Layered Liposomal System for Skin Delivery of Ascorbic Acid with Improved Chemical Stability
PMID:
36678619
DOI:
10.3390/ph16010121
Effect of hydrophilic and lipophilic vehicles on skin permeation of tegafur, alclofenac and ibuprofen with or without permeation enhancers
PMID:
7907514
DOI:
10.1248/bpb.16.1264
Review of the toxicologic properties of medium-chain triglycerides
PMID:
10685018
DOI:
10.1016/s0278-6915(99)00106-4
Comparison of adjuvant mechanisms of medium-chain triacylglycerol in a mouse FITC-induced contact hypersensitivity model
