Cocamidopropyl betaine

Functions
Surfactant
Cleansing agent
Thickener
Hair conditioning
Antistatic
Detergent
Foam booster
Viscosity controlling agent
CAS Number(s)
97862-59-4
61789-40-0
70851-07-9
83138-08-3
EINECS number(s)
263-058-8
274-923-4
FDA UNII
5OCF3O11KX
INCI name
Cocamidopropyl Betaine
Identifier
CIG-147

Cocamidopropyl betaine is a premium surfactant derived from coconut fatty acids and betaine. Betaine-derived surfactants are classified as amphoteric. Although their primary function in a surfactant system is to modify viscosity and foam properties, they also serve as substantive conditioners.

It is highly water-soluble in a wide pH range, pH 5 - 6 (10 % aqueous solution). Cocamidopropyl betaine is a clear yellow liquid with no or faint odor. It is a very mild co-surfactant (also useful as a primary surfactant) compatible with anionic, nonionic, and cationic surfactants. Thanks to its very low irritation potential it is used often as a replacement for part of the primary surfactant to decrease eye sting and irritation.

When adequately formulated, Cocamidopropyl betaine effectively reduces irritation commonly associated with primary anionic surfactants. In addition, it is a good cleanser, foam booster, viscosity enhancer, excellent conditioning & antistatic agent, and moderate emulsifier. Therefore, it is used as the primary thickener and surfactant in foaming and dilutable conditioners.

The unique properties of Cocamidopropyl betaine make it suitable for hair shampoos, hair conditioners, bath products, facial and skin cleansers, creams, and disinfectants, including baby products. Because it is a quaternary nitrogen compound, Cocamidopropyl betaine is often used at fairly low concentrations as a skin conditioner in shower gels.

When used with anionic surfactants such as SLES, Cocamidopropyl betaine can also boost foam while adding viscosity to a formulation.  In addition, it reduces the irritation of primary anionic surfactants; thus, it is especially well suited for low-irritation, high-foaming products. Moreover, its skin sensitization potential is very low; allergic reactions such as contact dermatitis are very rare.

Synonyms
CAPB
Changed

References

Final report of the Cosmetic Ingredient Review Expert Panel on the safety assessment of cocamidopropyl betaine (CAPB)
Author(s):
, , , , , , , , , ,
PMID:
22869896
DOI:
10.1177/1091581812447202
Cocamidopropyl betaine.
Author(s):
,
Journal:
Dermatitis (2008 May-Jun)
PMID:
18627690
Safety assessment of cocamidopropyl betaine, a cosmetic ingredient.
Author(s):
, , , , , , , , , ,
Journal:
Toxicol Res (2024 Jul)
PMID:
38911545
DOI:
PMC11187029
Is cocamidopropyl betaine a contact allergen? Analysis of network data and short review of the literature.
Author(s):
, , ,
Journal:
Contact Dermatitis (2011 Apr)
PMID:
21392028
DOI:
10.1111/j.1600-0536.2010.01863.x
Clinical allergy to cocamidopropyl betaine: reactivity to cocamidopropylamine and lack of reactivity to 3-dimethylaminopropylamine.
Author(s):
, , ,
Journal:
Contact Dermatitis (2001 Aug)
PMID:
11553115
DOI:
10.1034/j.1600-0536.2001.045002072.x
Infrared Spectroscopic Analysis Indicates That Cocamidopropyl Betaine Has Little Effect on the Stratum Corneum.
Author(s):
, ,
Journal:
J Oleo Sci (2026)
PMID:
41485899
DOI:
10.5650/jos.ess25210