βetavera®

Functions
Firming
Hydrating
Smoothing
Soothing

It has long been recognized that specific polysaccharides, mannans, contribute to the beneficial effects of Aloe vera. Concurrently, the activity of yeast-derived adjuvants, such as zymosan, has been determined to be a result of the mannans and glucans present.

βetavera ® combines the active polysaccharide fractions of both substances. Aloe Barbendensis Miller (Lilaceae) is widely used in cosmetics and herbal medicine for the treatment of topical disorders. As a material, Aloe vera has been extensively studied in terms of both its composition and efficacy. It is now generally accepted that the benefits of Aloe come not from a single component, but from the combination of all its components. It is the interrelationship of the different elements of Aloe that makes the water present critical. It is only in aqueous media that the full benefits of Aloe vera are realized.

Critical in the activity of Aloe vera are the mannose-based polysaccharides present. Specifically, partially acetylated β-1,4-mannans show high affinity for specific receptors on both macrophages and fibroblasts. Stimulation of these cells not only causes an increase in the production of collagen and proteoglycans but also increases the immune response. Concurrently, Aloe, because of its Salicylic Acid content, can inhibit prostaglandin and thromboxane formation by blocking the Arachidonic Acid Cascade.

Zymosan, traditionally used as an adjuvant, is isolated from the cell walls of yeast (Saccharomyces cerevisiae). Work done to reveal the composition of this material shows that it is composed of α-D-mannans and β-D-Glucans. Current research has shown that glucan particles enhance the ability of macrophages to distinguish foreign materials.

Currently, substantially purified β-1,3-glucans are being used in topical preparations to revitalize the skin. It has been demonstrated that β-1,3-glucans can smooth the skin, reduce redness, and minimize the appearance of fine lines. β-1,3-glucans have also been shown to increase macrophage activity significantly. The advantage of β-1,3-glucans derived from yeast over other glucans is the avidity with which they bind to the glucan receptor of the macrophage.

Ingredients

Aloe Barbadensis Leaf Extract
Yeast Extract

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