Ectoin

Functions
Protective
Photoprotective
Thermal protection
Hydrating
CAS Number(s)
96702-03-3
FDA UNII
7GXZ3858RY
INCI name
Ectoin
Identifier
CIG-866
Origin
Biotechnological

Ectoin is a natural cell protection factor discovered in halophilic bacteria, such as Ectothiorhodospira halochloris, which persist and propagate under extreme conditions in saltwater, the sea, and saline deserts. These halophilic bacteria are exposed to high UV irradiation, extreme temperatures, and high salinity.

Nevertheless, they adapt to these inhospitable conditions: their survival is guaranteed by a unique amino acid, namely Ectoin. The bacterial biopolymers are stabilized by producing Ectoin and protected against these damaging external stressors.

Ectoin improves the skin's water-retention capacity, has a hydrating and anti-inflammatory action, and stabilizes cellular structures by its protective effect on cell membranes. In addition, it enhances cell protection against damaging environmental factors and conditions, such as extreme temperatures, high salt concentrations, low humidity, and UV exposure.

Ectoin is also one of the best natural options available to stimulate skin cells' protective properties, like cell and immune system maintenance, and offers UVA protection. In addition, based on an in-vivo study, it can improve the tactile properties of skincare products.
Synonyms
Ectoine
Changed

References

Topical Ectoine: A Promising Molecule in the Upper Airways Inflammation-A Systematic Review
Author(s):
, , , , , , , , ,
PMID:
31534961
DOI:
10.1155/2019/7150942
Ectoine as a promising protective agent in humans and animals
Author(s):
,
PMID:
28033102
DOI:
10.1515/aiht-2016-67-2837
Ectoine as a multifunctional molecule: biotechnological production and pharmaceutical applications
Author(s):
, , , , , , , , ,
PMID:
41299111
DOI:
10.1007/s13346-025-02024-2
Topical Ectoine Application in Children and Adults to Treat Inflammatory Diseases Associated with an Impaired Skin Barrier: A Systematic Review
Author(s):
,
PMID:
35038127
DOI:
10.1007/s13555-021-00676-9