Isopropyl Cloprostenate

Functions
Hair growth stimulator
Eyelash care
Hair conditioning
CAS Number(s)
157283-66-4
FDA UNII
765298537G

Ophthalmologists have noticed that medical prostaglandin derivatives prescribed for the treatment of ocular hypertension and open-angle glaucoma share common side effects, including eyelash growth. Isopropyl Cloprostenate is a synthetic prostaglandin derivative used in the pharmaceutical industry as an artificial hair-growth hormone, stimulating hair follicles and promoting hair growth.

Isopropyl Cloprostenate effectively promotes lash growth and lengthens eyelashes, but as a biologically active drug, it has multiple adverse effects, which should be considered before using preparations containing this ingredient. Prostaglandins, with their hormone-like actions, affect almost all tissues.

Possible side effects of Isopropyl Cloprostenate include:

  • Change of iris (eye) color (increased pigmentation)
  • Enhanced pain sensitivity and itching
  • Shrinking of the eyelid adipocytes causes upper ptosis (eyelid drooping)
  • Increased prominence of eyelid vessels causing discolorations in the eye area
  • Prostaglandin-associated periorbitopathy
  • Excessive tearing
  • Inflammatory conditions, including uveitis, macular edema, and irritation.
  • High risk of eye infections and vision impairment.

Ingredients

Isopropyl cloprostenate
Synonyms
Latisse
Changed

References

Do Prostaglandin Analogue Lash Lengtheners Cause Eyelid Fat and Volume Loss?
Author(s):
, , , ,
PMID:
35700523
DOI:
10.1093/asj/sjac156
Periocular discoloration after using a prostaglandin analog for eyelash enhancement: evaluation with reflectance confocal microscopy
Author(s):
, , , , ,
PMID:
27595988
DOI:
10.1111/jocd.12281